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Citrus Aurantium Extract /hot Sale High Quality Antiinflammatory Citrus Aurantium Extract Bulk Diosmin Powder

Citrus Aurantium Extract /hot Sale High Quality Antiinflammatory Citrus Aurantium Extract Bulk Diosmin Powder

Product Name: Citrus Aurantium Extract (Diosmin)   Latin Name: Citrus aurantium L.   Part Used: Fruit   Appearance: Light Yellow Powder Active Ingredient:Diosmin    Specification:Diosmin   90%  Test Method:HPLC

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Product Details

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Diosmin is a naturally occurring flavonoid glycoside that can be isolated from various plant sources or derived from the flavonoid hesperidin. Diosmin is considered to be a vascular-protecting agent used to treat chronic venous insufficiency, hemorrhoids, lymphedema, and varicose veins. As a flavonoid, diosmin also exhibits anti-inflammatory, free-radical scavenging, and antimutagenic properties.

Diosmin differs molecularly from hesperidin by the presence of a double bond between two carbon atoms in diosmin's central carbon ring. Diosmin can be manufactured by extracting hesperidin from citrus rinds, followed by conversion of hesperidin to diosmin. Diosmin has been used for more than 30 years as a phlebotonic and vascular-protecting agent, and has recently begun to be investigated for other therapeutic purposes, including cancer, premenstrual syndrome, colitis, and diabetes.



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Product Name: Citrus Aurantium Extract  (Diosmin)

 

Latin Name:Citrus aurantium L.

 

Part Used: Fruit

 

Appearance: Light Yellow Powder

Active Ingredient:Diosmin 

 

Specification:Diosmin   90%

 

Particle Size: 100% pass 80mesh 

CAS No.:520-27-4

Molecular Formula: C28H32O15

Molecular Weight:608.54

 

Test Method:HPLC

   

Place of Origin: China 

  

Storage: Store in a cool & dry area, keep away from the direct light and heat.

  
Validity: Two years if properly stored.

  
Shelf Life: Two years under well storage situation and stored away from direct sun light.





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1.Diosmin prolongs the vasoconstrictor effect of norepinephrine on the vein wall, increasing venous tone, and therefore reducing venous capacitance, distensibility, and stasis.

2.Diosmin increases the venous return and reduces venous hyperpressure present in patients suffering from CVI.

3.Diosmin improves lymphatic drainage by increasing the frequency and intensity of lymphatic contractions, and by increasing the total number of functional lymphatic capillaries.

4.Diosmin with hesperidine decreases the diameter of lymphatic capillaries and the intralymphatic pressure.

5.At the microcirculation level, diosmin reduces capillary hyperpermeability and increases capillary resistance by protecting the microcirculation from damaging processes.

6.Diosmin reduces the expression of endothelial adhesion molecules,and inhibits the adhesion, migration, and activation of leukocytes at the capillary level.Diosmin leads to a reduction in the release of inflammatory mediators, principally oxygen free radicals and prostaglandins.



Applications.jpg

1.Micronized Diosmin is a biogenic amine derived by extracting hesperidin from Citrus Aurantium L., followed by conversion of hesperidin to diosmin.

2.Micronized Diosmin is considered to be a vascular-protecting agent used to treat chronic venous insufficiency, hemorrhoids, lymphedema, and varicose veins.As a flavonoid, Micronized Diosmin also exhibits anti-inflammatory, free-radical scavenging, and antimutagenic properties.

3.Micronized Diosmin has been used for more than 30 years as a phlebotonic and vascularprotecting agent, and has recently begun to be investigated for other therapeutic purposes, including cancer, premenstrual syndrome, colitis, and diabetes.



 

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